Advances in Nanoparticulate Drug Delivery Approaches for Sublingual and Buccal Administration

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Buccal and Sublingual Delivery of Nifedipine

Buccal Drug Delivery System

The buccal mucosa lines the inner cheek, and buccal formulations are placed in the mouth between the upper gingivae (gums) and cheek to treat local and systemic conditions. The buccal route provides one of the potential route for typically large, hydrophilic and unstable proteins, oligonucleotides and polysaccharides, as well as conventional small drug molecules. The oral cavity has been used a...

Comparison of misoprostol plasma concentrations following buccal and sublingual administration.

BACKGROUND New indications for misoprostol include medical abortion, cervical softening, induction of labor and treatment of postpartum hemorrhage. Various routes of misoprostol administration under study include oral, vaginal, buccal, sublingual and rectal. MATERIALS AND METHODS This was an open-label, randomized, cross-over study of the pharmacokinetic differences of buccal vs. sublingual m...